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Volume 359:1519-1521 October 2, 2008 Number 14
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Intensive Glucose Control in Type 2 Diabetes

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 by The Action to Control Cardiovascular Risk in Diabetes Study Group
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 by The ADVANCE Collaborative Group
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To the Editor: In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study (June 12 issue),1 the intensive-therapy group differed from the standard-therapy group not only in the glycated hemoglobin level achieved but also in the number of drug classes prescribed to achieve it. It is plausible that in the subgroup of patients with a baseline glycated hemoglobin level of 8% or less who had a benefit with intensive treatment, the target glycated hemoglobin level was achieved with fewer drug classes than in the subgroup of patients with a higher baseline glycated hemoglobin level. Thus, one wonders whether the . . . [Full Text of this Article]




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