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Published at www.nejm.org June 7, 2009 (10.1056/NEJMe0904090)

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The prevalence of diabetes mellitus is rising at an alarming rate and is projected to more than double by 2030.¹ The disease currently afflicts 171 million people worldwide, with 23.6 million in the United States. The adverse microvascular and macrovascular consequences of diabetes are well recognized, as is the accompanying accelerated rate of atherosclerosis that predisposes patients to coronary artery disease and to higher rates of myocardial infarction and death. Treatment strategies that are aimed at reducing these events have embraced both optimal medical therapy (lifestyle intervention, vigilant glycemic control, and aggressive secondary prevention) and interventional management (catheter-based and surgical . . . [Full Text of this Article]

Source Information

From the Department of Medicine, State University of New York at Buffalo Schools of Medicine and Public Health, Buffalo (W.E.B.); and Nuffield Department of Surgery, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom (D.P.T.).

This article (10.1056/NEJMe0904090) was published on June 7, 2009, at NEJM.org.

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